Once things get calmed down after the the battle with Frieza, Garlic Jr. returns from the Dead Zone to cause problems once again. He takes Kame and Mr. Popo hostage, and releases his Black Water Mist on the Earth. The evil mist causes people to becomes super violent and turn on one another. Piccolo tricks him into thinking he has been turned by the mist, in order to get close enough to Kame's prison in the bottle. Once the farce is unmasked Kame and Mr. Popo are freed and they take the Sacred Water, the only cure for the mist, to the 7 winds to spread them across the world.
Garlic Jr. escaped the Dead Zone by drawing power from the Makioh Star. The star powers his battle against Piccolo, Krillin, and Gohan. Eventually it comes down just like in the movie Dead Zone. Garlic Jr. once again tries to draw the heroes into the Dead Zone and once again Gohan thwarts his attack and bounces him into the Dead Zone instead.
With Garlic Jr. gone, there is one thing left. Krillin and Gohan go after a giant pearl to give Krillin's girlfriend, Marron. But during the quest for the pearl, Krillin realizes he has to let Marron go. The give up the chase on the pearl and return to the surface. Krillin let's Marron go and the Garlic Jr. Mini Series draws to a close.